Calviri, Inc. Receives Exclusive Patent License to Immunosignature Technology, Strengthening Its Disease Diagnostic Capabilities


Calviri, Inc., a biotech startup focused on ending deaths from cancer, announces that Skysong Innovations, the intellectual property management company for Arizona State University (“ASU”), granted Calviri an exclusive license to ASU’s Immunosignature patent portfolio. The portfolio consists of multiple granted and pending patents for the use and optimization of immunosignatures as an antibody-based diagnostic platform in the United States and the rest of the world.

The Immunosignature Technology was invented and originally developed by Stephen Albert Johnston, now CEO of Calviri, and his colleagues at ASU. The platform uses hundreds of thousands of chemically diverse peptides to provide an unbiased profile of an individual’s antibody repertoire. It has been applied to both infectious and chronic diseases in published reports. Initially intended as simply a diagnostic tool to detect disease onset, additional work has shown its potential for measuring disease severity and response to therapies.

“Adding the Immunosignature Platform to Calviri’s Frameshift Peptide Technology provides Calviri with a broadened, powerful set of scientific tools in diagnostics and vaccine development,” said Johnston, CEO of Calviri. “From a small volume of blood, we may be able to detect diseases such as cancer, Alzheimer’s and infections at early stages. A sensitive test for SARS-CoV-2 antibodies is also currently under development.”

“Calviri is dedicated to detecting and treating disease early,” said Dr. Kathryn Sykes, VP of Research and Product Development. “Until now, we have focused on the early detection of cancers with our Frameshift Peptide Technology and treatment with pre-made vaccines. With the addition of the Immunosignature Technology we can expand our mission to other diseases.”

“We are enthusiastic about Calviri and its ability to develop important commercial products with this promising, highly innovative ASU technology,” said Kyle Siegal, Senior VP at Skysong Innovations.

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Strengthening Science, Technology and Innovation Systems for Sustainable Development in Africa


On 7 October 2020, UNESCO, represented by Mr. Jean-Yves Le Saux, Director of the Bureau of Strategic Planning, and Sweden, represented by Mr Mikael Schultz, Deputy Permanent Delegate of Sweden to UNESCO, signed a pathbreaking agreement to support science, technology and innovation in Africa. Shamila Nair-Bedouelle, Assistant Director General for the Natural Science Sector and Magnus Magnusson, representing Gabriela Ramos, Assistant Director General for the Social and Human Science Sector, Pia Engstrand, Sida’s focal point for UNESCO (through virtual connection) were also present at the ceremony and will jointly oversee the implementation of this initiative.

The Swedish International Development Agency (Sida) will provide funding in the amount of 25 million Swedish kronor over two years (2020-2022) to support the first phase of a major initiative within UNESCO’s global framework for monitoring, policy support and advocacy for the Recommendation on Science and Scientific Researchers, adopted by the General Conference in 2017.

Focusing on African needs and priorities and in line with the African Union Agenda 2063 ‘The Africa we want”, the Sida funding will support UNESCO in strengthening science, technology and innovation systems and governance in selected African countries.

Science, technology and innovation (STI) are universally recognized as key drivers for poverty eradication and essential components for achieving the Sustainable Development Goals (SDGs). However, to make STI work for the society, appropriate STI policy frameworks and participatory forms of governance need to be developed and reinforced. In this regard, UNESCO supports countries’ efforts to reform and upgrade national STI systems and governance. Ultimately, stronger science, technology and innovation systems will enable African societies to attain greater inclusivity and resilience through enhanced capacity to achieve the Sustainable Development Goals and the African Union 2063 Development Agenda. The aim is to identify effective approaches, mechanisms, strategies and policies for applying science, technology and